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Alternative name
TRMT5, tRNA methyltransferase 5, TRM5, tRNA [GM37] methyltransferase, M1G methyltransferase antibody
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Catalog
A009007
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,WB
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PurificationImmunogen affinity purified
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ImmunogenTRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
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Western BlotJurkat cells were subjected to SDS PAGE followed by western blot with A009007(TRMT5 antibody) at dilution of 1:500
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Recommended dilutionWB:1:500-1:5000
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Product Description specificalInvolved in mitochondrial tRNA methylation (PubMed:26189817). Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
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Gene nameTRMT5
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Uniprot IDQ32P41
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Calculated M.W.58kDa
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Observed M.W.50-55kd
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