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Alternative name
TRIP4, TRIP 4, TR interacting protein 4, ASC 1, HsT17391 antibody
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Catalog
A008998
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,WB
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PurificationImmunogen affinity purified
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Immunogenthyroid hormone receptor interactor 4
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Western BlotHL-60 cells were subjected to SDS PAGE followed by western blot with A008998(TRIP4 antibody) at dilution of 1:1000
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Recommended dilutionWB:1:500-1:5000
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Product Description specificalTranscription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation (PubMed:10454579, PubMed:25219498). Also involved in androgen receptor transactivation (By similarity). Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF- kappa-B (PubMed:12077347). May play a role in the development of neuromuscular junction (PubMed:26924529).
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Gene nameTRIP4
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Uniprot IDQ15650
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Calculated M.W.66kDa
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Observed M.W.60-65kd
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