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Alternative name
16E1 BP, 16E1BP, PCH2, TR interacting protein 13, TRIP 13, TRIP13 antibody
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Catalog
A008997
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IP
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PurificationImmunogen affinity purified
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Immunogenthyroid hormone receptor interactor 13
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Western BlotJurkat cells were subjected to SDS PAGE followed by western blot with A008997(TRIP13 antibody) at dilution of 1:400
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Recommended dilutionWB::500-1:5000
IP:1:200-1:1000
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Product Description specificalPlays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double- strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity).
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Gene nameTRIP13
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Uniprot IDQ15645
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Calculated M.W.49kDa
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Observed M.W.49 kDa
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