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Alternative name
TRIM37, POB1, TEF3, MUL, tripartite motif containing 37 antibody
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Catalog
A008982
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,WB
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PurificationImmunogen affinity purified
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Immunogentripartite motif-containing 37
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Western BlotPC-3 cells were subjected to SDS PAGE followed by western blot with A008982(TRIM37 antibody) at dilution of 1:300
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Recommended dilutionWB:1:500-1:5000
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Product Description specificalE3 ubiquitin-protein ligase required to prevent centriole reduplication (PubMed:15885686, PubMed:23769972). Probably acts by ubiquitinating positive regulators of centriole reduplication (PubMed:23769972). Mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes (PubMed:25470042). Has anti-HIV activity (PubMed:24317724).
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Gene nameTRIM37
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Uniprot IDO94972
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Calculated M.W.89kDa
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Observed M.W.89kd
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