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Alternative name
LOQS, TAR RNA binding protein 2, TARBP2, TRBP, TRBP1, TRBP2 antibody
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Catalog
A008956
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF,IP
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PurificationImmunogen affinity purified
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ImmunogenTAR (HIV-1) RNA binding protein 2
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IHCImmunohistochemistry of paraffin-embedded human brain using A008956(TRBP antibody) at dilution of 1:100
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Western BlotHepG2 cells were subjected to SDS PAGE followed by western blot with A008956(TRBP antibody) at dilution of 1:1000
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Recommended dilutionWB:1:500-1:5000;IP:1:500-1:5000;IHC:1:20-1:200;IF:1:10-1:100
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Product Description specificalTARBP2 is a component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC). Within the complex, TARBP2 and DICER1 are required to process precursor miRNAs (pre-miRNA) to mature miRNA and then load them onto EIF2C2/AGO2. It may has a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1. Otherwise, it binds to the HIV-1 TAR RNA that is located in the long terminal repeat (LTR) of HIV-1, and stimulates translation of TAR-containing RNAs.
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Gene nameTARBP2
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Uniprot IDQ15633
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Calculated M.W.39kDa,observed 45kDa
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Observed M.W.43-46 kDa
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