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Alternative name
HSP75 antibody
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Catalog
A008941
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF,FC
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PurificationImmunogen affinity purified
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ImmunogenTNF receptor-associated protein 1
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IHCImmunohistochemistry of paraffin-embedded human heart using A008941(TRAP1 antibody) at dilution of 1:50
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Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A008941(TRAP1 antibody) at dilution of 1:800
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Recommended dilutionWB:1:500-1:5000;IHC:1:20-1:200;IF:1:10-1:100
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Product Description specificalChaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.
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Gene nameTRAP1
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Uniprot IDQ12931
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Calculated M.W.80kDa
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Observed M.W.66-70 kDa ,60 kDa
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