StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Species ReactivityHuman,Mouse ,Rat
PurificationImmunogen affinity purified
Immunogentranscription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
IHCImmunohistochemistry of paraffin-embedded human breast cancer tissue slide using A008619( TFAP2C Antibody) at dilution of 1:400 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A008619(TFAP2C antibody) at dilution of 1:1000
Recommended dilutionWB : 1:500-1:5000
Product Description specificalSequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.