StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Species ReactivityHuman,Rat, Mouse
PurificationImmunogen affinity purified
Immunogenbrain-derived neurotrophic factor
IHCImmunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using A000859( BDNF Antibody) at dilution of 1:200
Western Blotfetal human brain tissue were subjected to SDS PAGE followed by western blot with A000859( BDNF Antibody) at dilution of 1:300
Recommended dilutionWB : 1:200-1:1000
Product Description specificalDuring development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.