StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Species ReactivityHuman,Mouse ,Rat
PurificationImmunogen affinity purified
Immunogentudor domain containing 3
IHCImmunohistochemistry of paraffin-embedded mouse testis tissue slide using 25239-1-AP( TDRD5 Antibody) at dilution of 1:50
Western Blotmouse testis tissue were subjected to SDS PAGE followed by western blot with 25239-1-AP( TDRD5 Antibody) at dilution of 1:300
Recommended dilutionWB : 1:500-1:5000
Product Description specificalScaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine- methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins.