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Alternative name
SPO11, CT35, Cancer/testis antigen 35 antibody
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Catalog
A008184
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB
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PurificationImmunogen affinity purified
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ImmunogenSPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalComponent of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles. Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2.
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Gene nameSPO11
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Uniprot IDQ9Y5K1
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Observed M.W.55-70 kDa
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