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Alternative name
ANOP3, MCOPS3, SOX2, Transcription factor SOX 2 antibody
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Catalog
A008125
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat,Zebrafish
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Applications Tested/SuitableELISA,IF,WB,IHC
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PurificationImmunogen affinity purified
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ImmunogenSRY (sex determining region Y)-box 2
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IHCImmunohistochemistry of paraffin-embedded mouse embryo tissue slide using A008125( SOX2 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
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Western Blotmouse brain tissue were subjected to SDS PAGE followed by western blot with A008125(SOX2 antibody) at dilution of 1:600
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalTranscription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
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Gene nameSOX2
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Uniprot IDP48431
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Observed M.W.37-40 kDa
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