-
Alternative name
KIAA0064 antibody
-
Catalog
A008084
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IF,IHC,IP
-
PurificationImmunogen affinity purified
-
Immunogensorting nexin 17
-
IHCImmunohistochemistry of paraffin-embedded human brain tissue slide using A008084( SNX17 Antibody) at dilution of 1:50
-
Western Blothuman brain tissue were subjected to SDS PAGE followed by western blot with A008084(SNX17 antibody) at dilution of 1:300
-
Recommended dilutionWB : 1:200-1:2000
-
Product Description specificalCritical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).
-
Gene nameSNX17
-
Uniprot IDQ15036
-
Observed M.W.50 kDa
-