-
Alternative name
SNRPA, U1 A, U1 snRNP A, U1A antibody
-
Catalog
A008068
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IHC
-
PurificationImmunogen affinity purified
-
Immunogensmall nuclear ribonucleoprotein polypeptide A
-
IHCImmunohistochemistry of paraffin-embedded human cervical cancer tissue slide using A008068( SNRPA Antibody) at dilution of 1:50
-
Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A008068( SNRPA Antibody) at dilution of 1:600
-
Recommended dilutionWB : 1:200-1:2000
-
Product Description specificalComponent of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs.
-
Gene nameSNRPA
-
Uniprot IDP09012
-
Observed M.W.31 kDa
-