anti-SMYD2 antibody

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  • Alternative name

    KMT3C antibody

  • Catalog
    A008048
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman, Mouse
  • Applications Tested/SuitableELISA,WB,IF,IHC
  • PurificationImmunogen affinity purified
  • ImmunogenSET and MYND domain containing 2
  • IHCImmunohistochemistry of paraffin-embedded human heart using A008048(SMYD2 antibody) at dilution of 1:100
  • Western Blotmouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with A008048(SMYD2 antibody) at dilution of 1:500
  • Recommended dilutionWB : 1:500-1:5000
  • Product Description specificalProtein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.
  • Gene nameSMYD2
  • Uniprot IDQ9NRG4
  • Observed M.W.50kd


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