anti-SMURF1 antibody

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  • Alternative name

    KIAA1625 antibody

  • Catalog
    A008046
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman,Mouse ,Rat
  • Applications Tested/SuitableELISA,WB,IHC
  • PurificationImmunogen affinity purified
  • ImmunogenSMAD specific E3 ubiquitin protein ligase 1
  • IHCImmunohistochemistry of paraffin-embedded human colon cancer tissue slide using A008046( SMURF1 Antibody) at dilution of 1:50
  • Western BlotHEK-293 cells were subjected to SDS PAGE followed by western blot with A008046(SMURF1 antibody) at dilution of 1:800
  • Recommended dilutionWB : 1:200-1:2000
  • Product Description specificalE3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Plays a role in dendrite formation by melanocytes (PubMed:23999003).
  • Gene nameSMURF1
  • Uniprot IDQ9HCE7
  • Observed M.W.83-90 kDa


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