StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Species ReactivityHuman,Mouse ,Rat
PurificationImmunogen affinity purified
ImmunogenBAI1-associated protein 2
IHCImmunohistochemistry of paraffin-embedded human breast cancer using A000793(BAIAP2 antibody) at dilution of 1:100
Western Blotmouse brain tissue were subjected to SDS PAGE followed by western blot with A000793( BAIAP2 Antibody) at dilution of 1:600
Product Description specificalAdapter protein that links membrane-bound small G- proteins to cytoplasmic effector proteins. Necessary for CDC42- mediated reorganization of the actin cytoskeleton and for RAC1- mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.