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Alternative name
DKFZp434K2235, FLJ90319, KIAA0700, SIN3A antibody
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Catalog
A007870
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IF,IP
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PurificationImmunogen affinity purified
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ImmunogenSIN3 homolog A, transcription regulator (yeast)
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalActs as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in he control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation.
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Gene nameSIN3A
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Uniprot IDQ96ST3
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Observed M.W.150 kDa
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