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Alternative name
HHG 1, HHG1, HLP3, HPE3, MCOPCB5, SHH, SMMCI, Sonic hedgehog protein, TPT, TPTPS antibody
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Catalog
A007847
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IF,IHC,IP
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PurificationImmunogen affinity purified
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Immunogensonic hedgehog homolog (Drosophila)
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IHCImmunohistochemistry of paraffin-embedded mouse kidney tissue slide using A007847( SHH Antibody) at dilution of 1:50
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Western Blotmouse liver tissue were subjected to SDS PAGE followed by western blot with A007847(SHH antibody) at dilution of 1:800
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalIntercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior- posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity).
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Gene nameSHH
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Uniprot IDQ15465
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Observed M.W.50 kDa
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