anti-BACE1 antibody

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  • Alternative name

    BACE, KIAA1149 antibody

  • Catalog
    A000781
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman, Mouse , Zebrafish
  • Applications Tested/SuitableELISA,WB,IP,IHC
  • PurificationImmunogen affinity purified
  • Immunogenbeta-site APP-cleaving enzyme 1
  • IHCImmunohistochemistry of paraffin-embedded mouse brain tissue slide using A000781( BACE1 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
  • Western Blotmouse brain tissue were subjected to SDS PAGE followed by western blot with A000781(BACE1 antibody) at dilution of 1:500
  • Recommended dilutionWB : 1:200-1:2000
  • Product Description specificalResponsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
  • Gene nameBACE1
  • Uniprot IDP56817
  • Observed M.W.70-75 kDa




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