Product Categories
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Alternative name
SAP114 antibody
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Catalog
A007774
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF
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PurificationImmunogen affinity purified
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Immunogensplicing factor 3a, subunit 1, 120kDa
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IHCImmunohistochemistry of paraffin-embedded human breast cancer using A007774(SF3A1 antibody) at dilution of 1:400
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Western BlotK-562 cells were subjected to SDS PAGE followed by western blot with A007774(SF3A1 antibody) at dilution of 1:1000
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Recommended dilutionWB : 1:1000-1:10000
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Product Description specificalSubunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.
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Gene nameSF3A1
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Uniprot IDQ15459
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Observed M.W.120-130 kDa
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