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Alternative name
bA465E19.1, Rag B, RAGB, Ras related GTP binding B, RRAGB antibody
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Catalog
A007488
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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ImmunogenRas-related GTP binding B
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IHCImmunohistochemistry of paraffin-embedded human brain tissue slide using A007488( RRAGB Antibody) at dilution of 1:50
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Western Blothuman testis tissue were subjected to SDS PAGE followed by western blot with A007488(RRAGB antibody) at dilution of 1:500
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalGuanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates to the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.
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Gene nameRRAGB
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Uniprot IDQ5VZM2
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Observed M.W.40 kDa
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