anti-RENALASE antibody

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  • Alternative name

    C10orf59, MAO C, Monoamine oxidase C, RENALASE, RNLS antibody

  • Catalog
    A007238
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman,Mouse ,Rat
  • Applications Tested/SuitableELISA,WB,IHC,IP
  • PurificationImmunogen affinity purified
  • Immunogenchromosome 10 open reading frame 59
  • IHCImmunohistochemistry of paraffin-embedded human kidney using A007238(RENALASE antibody) at dilution of 1:100
  • Western Blothuman heart tissue were subjected to SDS PAGE followed by western blot with A007238(RENALASE antibody) at dilution of 1:500
  • Recommended dilutionWB:1:500-1:5000;IHC:1:20-1:200;IP:1:200-1:2000
  • Product Description specificalRNLS, also named as Renalase, C10orf59 and MAO-C, belongs to the renalase family. It is probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. RNLS degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. It lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis. RNLS has physiologically relevant catecholamine-oxidizing activity. (PMID:15841207 ) This antibody is specific to RNLS.
  • Gene nameC10orf59
  • locationSecreted
  • Uniprot IDQ5VYX0
  • Calculated M.W.35kDa
  • Observed M.W.35 kDa


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