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Alternative name
ARA24 antibody
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Catalog
A007100
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,IHC,IF,IP,WB
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PurificationImmunogen affinity purified
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ImmunogenRAN, member RAS oncogene family
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IHCImmunohistochemistry of paraffin-embedded human breast cancer tissue slide using A007100( RAN Antibody) at dilution of 1:50
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Western BlotHEK-293 cells were subjected to SDS PAGE followed by western blot with A007100( RAN Antibody) at dilution of 1:1000
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalGTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Acts as a negative regulator of the kinase activity of VRK1 and VRK2. _x000D_Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.
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Gene nameRAN
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Uniprot IDP62826
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Observed M.W.24 kDa
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