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Alternative name
FLJ14660, FLJ22548, Rab 3A interacting protein, Rab3A interacting protein, RAB3IP, Rabin 3, RABIN3, Rabin8, SSX2 interacting protein antibody
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Catalog
A007033
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF,IP
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PurificationImmunogen affinity purified
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ImmunogenRAB3A interacting protein (rabin3)
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IHCImmunohistochemistry of paraffin-embedded human pancreas cancer using A007033(RABIN8 antibody) at dilution of 1:50
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Western Blothuman brain tissue were subjected to SDS PAGE followed by western blot with A007033(RABIN8 antibody) at dilution of 1:2000
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Recommended dilutionWB:1:1000-1:10000
IP:1:500-1:5000
IHC:1:20-1:200
IF:1:10-1:100
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Product Description specificalGuanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP- bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.
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Uniprot IDQ96QF0
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Calculated M.W.56kDa
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