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Alternative name
RAB1C, RAY antibody
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Catalog
A007019
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IP,IHC,IF
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PurificationImmunogen affinity purified
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ImmunogenRAB35, member RAS oncogene family
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IHCImmunohistochemistry of paraffin-embedded human brain tissue slide using A007019( RAB35 Antibody) at dilution of 1:50
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Western Blothuman brain tissue were subjected to SDS PAGE followed by western blot with A007019(RAB35 antibody) at dilution of 1:600
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalThe small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in the process of endocytosis and is an essential rate-limiting regulator of the fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localization at the intercellular bridge. May indirectly regulate neurite outgrowth.
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Gene nameRAB35
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Uniprot IDQ15286
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Observed M.W.23 kDa
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