-
Alternative name
RAB1 antibody
-
Catalog
A007000
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,IHC,WB
-
PurificationImmunogen affinity purified
-
ImmunogenRAB1A, member RAS oncogene family
-
IHCImmunohistochemistry of paraffin-embedded human pancreas cancer using A007000(RAB1A antibody) at dilution of 1:50
-
Western Blotmouse brain tissue were subjected to SDS PAGE followed by western blot with A007000( RAB1A Antibody) at dilution of 1:1000
-
Recommended dilutionWB : 1:500-1:5000
-
Product Description specificalThe small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion. Regulates the level of CASR present at the cell membrane. Plays a role in cell adhesion and cell migration, via its role in protein trafficking. Plays a role in autophagosome assembly and cellular defense reactions against pathogenic bacteria. Plays a role in microtubule-dependent protein transport by early endosomes and in anterograde melanosome transport.
-
Gene nameRAB1A
-
Uniprot IDP62820
-
Observed M.W.23 kDa
-