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Alternative name
5 Lipoxygenase, 5 LO, 5 LOX, 5LPG, ALOX5, LOG5 antibody
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Catalog
A000007
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,IF,WB
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PurificationImmunogen affinity purified
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Immunogenarachidonate 5-lipoxygenase
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Western BlotHL-60 cells were subjected to SDS PAGE followed by western blot with A000007( ALOX5 Antibody) at dilution of 1:600
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Recommended dilutionWB : 1:200-1:2000;IF : 1:20-1:100
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Product Description specificalALOX5(arachidonate 5-lipoxygenase) is also named as LOG5, 5-LO and belongs to the lipoxygenase family. It catalyzes the first step in leukotriene biosynthesis, and plays a role in inflammatory processes. It is a 78 kDa iron-containing enzyme that translocates from the cytosol to associate with FLAP, and converts arachidonate in two steps into the unstable intermediate LTA4. It is essential for cysteinyl-leukotriene (cys-LT) production, critical mediators in asthma(PMID:12911785).
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Gene nameALOX5
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Uniprot IDP09917
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Calculated M.W.75kDa
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Observed M.W.~70 kDa
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