anti-5 Lipoxygenase antibody

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  • Alternative name

    5 Lipoxygenase, 5 LO, 5 LOX, 5LPG, ALOX5, LOG5 antibody

  • Catalog
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman, Mouse
  • Applications Tested/SuitableELISA,IF,WB
  • PurificationImmunogen affinity purified
  • Immunogenarachidonate 5-lipoxygenase
  • Western BlotHL-60 cells were subjected to SDS PAGE followed by western blot with A000007( ALOX5 Antibody) at dilution of 1:600
  • Recommended dilutionWB : 1:200-1:2000;IF : 1:20-1:100
  • Product Description specificalALOX5(arachidonate 5-lipoxygenase) is also named as LOG5, 5-LO and belongs to the lipoxygenase family. It catalyzes the first step in leukotriene biosynthesis, and plays a role in inflammatory processes. It is a 78 kDa iron-containing enzyme that translocates from the cytosol to associate with FLAP, and converts arachidonate in two steps into the unstable intermediate LTA4. It is essential for cysteinyl-leukotriene (cys-LT) production, critical mediators in asthma(PMID:12911785).
  • Gene nameALOX5
  • Uniprot IDP09917
  • Calculated M.W.75kDa
  • Observed M.W.~70 kDa

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