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Alternative name
PEZ, PTPD2 antibody
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Catalog
A006933
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogenprotein tyrosine phosphatase, non-receptor type 14
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IHCImmunohistochemistry of paraffin-embedded human placenta using A006933(PTPN14 antibody) at dilution of 1:50
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Western BlotK-562 cells were subjected to SDS PAGE followed by western blot with A006933(PTPN14 antibody) at dilution of 1:400
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalProtein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell- matrix adhesion, cell migration, cell growth and also regulates TGF-beta gene expression, thereby modulating epithelial- mesenchymal transition. Mediates beta-catenin dephosphorylation at adhesion junctions. Acts as a negative regulator of the oncogenic property of YAP, a downstream target of the hippo pathway, in a cell density-dependent manner. May function as a tumor suppressor.
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Gene namePTPN14
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Uniprot IDQ15678
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Observed M.W.150 kDa
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