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Alternative name
MOSP, PLIP antibody
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Catalog
A006931
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogenprotein tyrosine phosphatase, mitochondrial 1
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IHCImmunohistochemistry of paraffin-embedded human pancreas cancer using A006931(PTPMT1 antibody) at dilution of 1:50
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Western Blotmouse pancreas tissue were subjected to SDS PAGE followed by western blot with A006931(PTPMT1 antibody) at dilution of 1:300
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Recommended dilutionWB : 1:200-1:1000
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Product Description specificalLipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells (By similarity).
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Gene namePTPMT1
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Uniprot IDQ8WUK0
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Observed M.W.21-23 kDa
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