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Alternative name
PTP 1B, PTP1B, PTPN1 antibody
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Catalog
A006927
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IF,IP
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PurificationImmunogen affinity purified
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Immunogenprotein tyrosine phosphatase, non-receptor type 1
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IHCImmunohistochemistry of paraffin-embedded human prostate cancer using A006927(PTPN1 antibody) at dilution of 1:50
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Western Blotjurkat cells were subjected to SDS PAGE followed by western blot with A006927(PTPN1 antibody) at dilution of 1:300
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Recommended dilutionWB:1:500-1:5000;IP:1:200-1:2000;IHC:1:20-1:200;IF:1:10-1:100
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Product Description specificalPTPN1(protein tyrosine phosphatase, non-receptor type 1) is also named as PTP1B, PTP-1B and belongs to the protein-tyrosine phosphatase family and non-receptor class 1 subfamily. PTPN1 is involved in the regulation of several important physiological pathways, which regulates both insulin and leptin signaling, and interacts with the epidermal-and platelet-derived growth factor receptors(PMID:20101100). The gene might harbor variants influencing susceptibility to insulin resistance and type 2 diabetes(PMID:15919813).
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Gene namePTPN1
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locationEndoplasmic reticulum,Membrane
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Uniprot IDP18031
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Calculated M.W.50kDa
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Observed M.W.45-55 kDa
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