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Alternative name
PP2A alpha, PP2Ac, PP2CA, PPP2CA, Replication protein C, RP C antibody
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Catalog
A006712
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,IP
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PurificationImmunogen affinity purified
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Immunogenprotein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
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IHCImmunohistochemistry of paraffin-embedded human liver cancer using A006712(PPP2CA antibody) at dilution of 1:50
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Western Blothuman liver tissue were subjected to SDS PAGE followed by western blot with A006712(PPP2CA antibody) at dilution of 1:300
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalPP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.
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Gene namePPP2CA
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Uniprot IDP67775
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Observed M.W.36 kDa
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