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Alternative name
PP2CB antibody
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Catalog
A006685
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogenprotein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform
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IHCImmunohistochemistry of paraffin-embedded human breast cancer tissue slide using A006685( PPM1B Antibody) at dilution of 1:200
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Western BlotMCF7 cells were subjected to SDS PAGE followed by western blot with A006685(PPM1B antibody) at dilution of 1:400
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalEnzyme with a broad specificity. Dephosphorylates CDK2 and CDK6 in vitro. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser- 172'. Plays an important role in the termination of TNF-alpha- mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
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Gene namePPM1B
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Uniprot IDO75688
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Observed M.W.50-53 kDa
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