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Alternative name
RPC11 antibody
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Catalog
A006634
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,IHC,IF,WB
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PurificationImmunogen affinity purified
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Immunogenpolymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
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IHCImmunohistochemistry of paraffin-embedded human gliomas using A006634(POLR3K antibody) at dilution of 1:100
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Western BlotTransfected HEK-293 cells were subjected to SDS PAGE followed by western blot with A006634( POLR3K Antibody) at dilution of 1:1000
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalDNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
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Gene namePOLR3K
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Uniprot IDQ9Y2Y1
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