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Alternative name
APPD, LAPF, ZFYVE15 antibody
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Catalog
A006540
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IF,IHC
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PurificationImmunogen affinity purified
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Immunogenpleckstrin homology domain containing, family F (with FYVE domain) member 1
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IHCImmunohistochemistry of paraffin-embedded human brain slide using A006540( PLEKHF1 Antibody) at dilution of 1:50
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Western Blothuman skeletal muscle tissue were subjected to SDS PAGE followed by western blot with A006540(PLEKHF1 antibody) at dilution of 1:500
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalMay induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase- independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.
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Gene namePLEKHF1
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Uniprot IDQ96S99
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Observed M.W.31kd
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