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Alternative name
PKC gamma, PKCC, PKCG, PRKCG, Protein kinase C gamma type, protein kinase C, gamma, SCA14 antibody
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Catalog
A006485
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC,FC,IP
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PurificationImmunogen affinity purified
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Immunogenprotein kinase C, gamma
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IHCImmunohistochemistry of paraffin-embedded human cerebellum tissue slide using A006485( PRKCG Antibody) at dilution of 1:200
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Western Blothuman brain tissue were subjected to SDS PAGE followed by western blot with A006485(PRKCG antibody) at dilution of 1:1000
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Recommended dilutionWB : 1:500-1:5000;IP : 1:200-1:2000;IHC : 1:20-1:200;IF : 1:50-1:500
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Product Description specificalProtein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC gamma is a neuron-specific member of the classical PKCs and is activated and translocated to subcellular regions as a result of various stimuli, including diacylglycerol synthesis, increased intracellular Ca(2+) and phorbol esters. Defects in this protein have been associated with spinocerebellar ataxia type 14 (SCA14), an autosomal dominant neurodegenerative disease.
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Gene namePRKCG
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Uniprot IDP05129
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Calculated M.W.78kDa
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Observed M.W.76-80 kDa
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