StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Species ReactivityHuman,Mouse ,Rat
PurificationImmunogen affinity purified
Immunogenasialoglycoprotein receptor 1
IHCImmunohistochemistry of paraffin-embedded human liver tissue slide using A000635( ASGR1 Antibody) at dilution of 1:200
Western Blothuman liver tissue were subjected to SDS PAGE followed by western blot with A000635(ASGR1 antibody) at dilution of 1:500
Recommended dilutionWB : 1:200-1:2000
Product Description specificalMediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.