anti-PDCD4 antibody

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  • Alternative name

    H731 antibody

  • Catalog
    A006239
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman,Mouse ,Rat
  • Applications Tested/SuitableELISA,WB,IHC,FC,IP
  • PurificationImmunogen affinity purified
  • Immunogenprogrammed cell death 4 (neoplastic transformation inhibitor)
  • IHCImmunohistochemistry of paraffin-embedded human breast cancer using A006239(PDCD4 antibody) at dilution of 1:50
  • Western BlotHeLa cells were subjected to SDS PAGE followed by western blot with A006239(PDCD4 antibody) at dilution of 1:3000
  • Recommended dilutionWB : 1:1000-1:10000
  • Product Description specificalInhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity).
  • Gene namePDCD4
  • Uniprot IDQ53EL6
  • Observed M.W.54-64 kDa




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