anti-PAK6 antibody

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  • Alternative name

    PAK5 antibody

  • Catalog
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman,Mouse ,Rat
  • Applications Tested/SuitableELISA,WB,IHC
  • PurificationImmunogen affinity purified
  • Immunogenp21 protein (Cdc42/Rac)-activated kinase 6
  • IHCImmunohistochemistry of paraffin-embedded human prostate cancer using A006124(PAK6 antibody) at dilution of 1:100
  • Western BlotPC-3 cells were subjected to SDS PAGE followed by western blot with A006124(PAK6 antibody) at dilution of 1:400
  • Recommended dilutionWB : 1:500-1:5000
  • Product Description specificalSerine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription. Inhibits also ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. May protect cells from apoptosis through phosphorylation of BAD.
  • Gene namePAK6
  • Uniprot IDQ9NQU5
  • Observed M.W.60 kDa

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