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Alternative name
PACSIN2, SDPII, Syndapin 2 antibody
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Catalog
A006101
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,IHC,WB,IP
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PurificationImmunogen affinity purified
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Immunogenprotein kinase C and casein kinase substrate in neurons 2
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IHCImmunohistochemistry of paraffin-embedded human breast cancer tissue slide using A006101( PACSIN2 Antibody) at dilution of 1:400
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Western BlotNIH/3T3 cells were subjected to SDS PAGE followed by western blot with A006101( PACSIN2 Antibody) at dilution of 1:600
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalLipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle- mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.
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Gene namePACSIN2
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Uniprot IDQ9UNF0
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Observed M.W.60-65 kDa
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