-
Alternative name
EBP1 antibody
-
Catalog
A006093
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IHC,IF,FC
-
PurificationImmunogen affinity purified
-
Immunogenproliferation-associated 2G4, 38kDa
-
IHCImmunohistochemistry of paraffin-embedded human breast cancer using A006093(PA2G4 antibody) at dilution of 1:100
-
Western BlotJurkat cells were subjected to SDS PAGE followed by western blot with A006093(PA2G4 antibody) at dilution of 1:2000
-
Recommended dilutionWB : 1:1000-1:10000
-
Product Description specificalMay play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site) (By similarity). Regulates cell proliferation, differentiation, and survival. Isoform 1 suppresses apoptosis whereas isoform 2 promotes cell differentiation (By similarity).
-
Gene namePA2G4
-
Uniprot IDQ9UQ80
-
Observed M.W.42 kDa, 48 kDa
-