-
Alternative name
OMPHK2, SNARK antibody
-
Catalog
A005886
-
Size100μg
-
Formliquid
-
Purity≥95% as determined by SDS-PAGE
-
StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
-
ClonalityPolyclonal Antibody
-
Host Rabbit
-
Species ReactivityHuman,Mouse ,Rat
-
Applications Tested/SuitableELISA,WB,IHC,IF
-
PurificationImmunogen affinity purified
-
ImmunogenNUAK family, SNF1-like kinase, 2
-
IHCImmunohistochemistry of paraffin-embedded human kidney using A005886(NUAK2 antibody) at dilution of 1:50
-
Western BlotY79 cells were subjected to SDS PAGE followed by western blot with A005886(NUAK2 antibody) at dilution of 1:400
-
Recommended dilutionWB : 1:200-1:2000
-
Product Description specificalStress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95- activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.
-
Gene nameNUAK2
-
Uniprot IDQ9H093
-
Observed M.W.70 kDa
-