StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Species ReactivityHuman, Mouse
PurificationImmunogen affinity purified
Immunogennephronophthisis 3 (adolescent)
IHCImmunohistochemistry of paraffin-embedded human heart tissue slide using A005816( NPHP3 Antibody) at dilution of 1:50
Western Blothuman testis tissue were subjected to SDS PAGE followed by western blot with A005816(NPHP3 antibody) at dilution of 1:500
Recommended dilutionWB : 1:200-1:2000
Product Description specificalRequired for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.