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Alternative name
NGB, neuroglobin antibody
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Catalog
A005718
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse ,Rat
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogenneuroglobin
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IHCImmunohistochemistry of paraffin-embedded human pancreas cancer using A005718(NGB antibody) at dilution of 1:100
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Western Blothuman brain tissue were subjected to SDS PAGE followed by western blot with A005718(NGB antibody) at dilution of 1:500
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalInvolved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis.
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Gene nameNGB
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Uniprot IDQ9NPG2
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Observed M.W.16kd
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