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Alternative name
Leucine zipper protein NF E2, NF E2, NFE2, p45, p45 NF E2 antibody
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Catalog
A005692
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman
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Applications Tested/SuitableELISA,WB,IHC,IF,IP
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PurificationImmunogen affinity purified
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Immunogennuclear factor (erythroid-derived 2), 45kDa
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IHCImmunohistochemistry of paraffin-embedded human colon cancer using A005692(NFE2 antibody) at dilution of 1:50
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Western BlotK-562 cells were subjected to SDS PAGE followed by western blot with A005692(NFE2 antibody) at dilution of 1:500
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalComponent of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
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Gene nameNFE2
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Uniprot IDQ16621
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Observed M.W.45 kDa
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