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Alternative name
BHLHA3, NEUROD antibody
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Catalog
A005674
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman,Mouse ,Rat
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Applications Tested/SuitableELISA,IHC,WB,IP
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PurificationImmunogen affinity purified
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Immunogenneurogenic differentiation 1
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IHCImmunohistochemistry of paraffin-embedded human pancreas cancer using A005674(NEUROD1 antibody) at dilution of 1:50
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Western BlotY79 cells were subjected to SDS PAGE followed by western blot with A005674(NEUROD1 antibody) at dilution of 1:200
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Recommended dilutionWB : 1:200-1:1000
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Product Description specificalActs as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5'-CANNTG-3'. Associates with the p300/CBP transcription coactivator complex to stimulate transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A. Contributes to the regulation of several cell differentiation pathways, like those that promote the formation of early retinal ganglion cells, inner ear sensory neurons, granule cells forming either the cerebellum or the dentate gyrus cell layer of the hippocampus, endocrine islet cells of the pancreas and enteroendocrine cells of the small intestine. Together with PAX6 or SIX3, is required for the regulation of amacrine cell fate specification. Also required for dendrite morphogenesis and maintenance in the cerebellar cortex. Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity).
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Gene nameNEUROD1
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Uniprot IDQ13562
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Observed M.W.50 kDa
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