anti-ARHGEF4 antibody

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  • Alternative name

    KIAA1112 antibody

  • Catalog
    A000562
  • Size100μg
  • Formliquid
  • Purity≥95% as determined by SDS-PAGE
  • StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
  • ClonalityPolyclonal Antibody
  • Host Rabbit
  • Species ReactivityHuman, Mouse
  • Applications Tested/SuitableELISA,IHC,WB
  • PurificationImmunogen affinity purified
  • ImmunogenRho guanine nucleotide exchange factor (GEF) 4
  • IHCImmunohistochemistry of paraffin-embedded human brain tissue slide using A000562( ARHGEF4 Antibody) at dilution of 1:50
  • Western Blotmouse brain tissue were subjected to SDS PAGE followed by western blot with A000562( ARHGEF4 Antibody) at dilution of 1:1000
  • Recommended dilutionWB : 1:500-1:5000
  • Product Description specificalActs as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
  • Gene nameARHGEF4
  • Uniprot IDQ9NR80
  • Observed M.W.72 kDa


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