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Alternative name
GRAF2 antibody
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Catalog
A000546
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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ImmunogenRho GTPase activating protein 10
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IHCImmunohistochemistry of paraffin-embedded human heart tissue slide using A000546( ARHGAP10 Antibody) at dilution of 1:200
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Western Blotmouse heart tissue were subjected to SDS PAGE followed by western blot with A000546( ARHGAP10 Antibody) at dilution of 1:1000
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalGTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).
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Gene nameARHGAP10
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Uniprot IDA1A4S6
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Observed M.W.89 kDa
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