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Alternative name
IFI 78K, IFI78, Interferon induced protein p78, MX, MX1, MxA, Myxovirus resistance protein 1 antibody
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Catalog
A005450
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IHC,IP
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PurificationImmunogen affinity purified
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Immunogenmyxovirus (influenza virus) resistance 1, interferon-inducible protein p78 ( Mouse )
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IHCImmunohistochemistry of paraffin-embedded human lung cancer slide using A005450( MX1 Antibody) at dilution of 1:50
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Western Blotmouse spleen tissue were subjected to SDS PAGE followed by western blot with A005450(MX1 antibody) at dilution of 1:300
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Recommended dilutionWB : 1:200-1:2000
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Product Description specificalInterferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.
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Gene nameMX1
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Uniprot IDP20591
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Observed M.W.76 kDa
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