StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Species ReactivityHuman, Mouse
PurificationImmunogen affinity purified
Immunogenmicrotubule-associated protein 1B
IHCImmunohistochemistry of paraffin-embedded mouse brain tissue slide using A004974( MAP1B Antibody) at dilution of 1:50
Western Blotmouse cerebellum tissue were subjected to SDS PAGE followed by western blot with A004974(MAP1B antibody) at dilution of 1:500
Recommended dilutionWB : 1:200-1:2000
Product Description specificalFacilitates tyrosination of alpha-tubulin in neuronal microtubules (By similarity). Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing.