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Alternative name
Amyloid like protein 1, APLP, APLP 1, APLP1 antibody
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Catalog
A000486
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Size100μg
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Formliquid
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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ClonalityPolyclonal Antibody
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Host Rabbit
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Species ReactivityHuman, Mouse
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Applications Tested/SuitableELISA,WB,IHC
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PurificationImmunogen affinity purified
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Immunogenamyloid beta (A4) precursor-like protein 1
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IHCImmunohistochemistry of paraffin-embedded human brain tissue slide using A000486( APLP1 Antibody) at dilution of 1:50
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Western Blotmouse brain tissue were subjected to SDS PAGE followed by western blot with A000486( APLP1 Antibody) at dilution of 1:1000
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Recommended dilutionWB : 1:500-1:5000
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Product Description specificalMay play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I. _x000D_The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis.
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Gene nameAPLP1
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Uniprot IDP51693
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Observed M.W.72 kDa
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